Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12857/115789
Title: The subtyping of primary aldosteronism by adrenal vein sampling: sequential blood sampling causes factitious lateralization
Authors: Rossitto, Giacomo 
Battistel, Michele 
Barbiero, Giulio 
Bisogni, Valeria 
Maiolino, Giuseppe 
Diego, Miotto
Seccia, Teresa M
Rossi, Gian Paolo 
Keywords: adrenal vein sampling;aldosterone;hypertension;lateralization;sequential;simultaneous
Keywords Plus: CLINICAL-PRACTICE GUIDELINE;SELECTIVITY;DIAGNOSIS;STIMULATION;ADENOMAS;CORTISOL;EXCESS
Mesh headings: Adrenal Cortex Neoplasms;Adrenocortical Adenoma;Aldosterone;Blood Specimen Collection;Hyperaldosteronism
Secondary Mesh headings: Adrenal Glands;Adult;Female;Humans;Male;Middle Aged;Veins
Issue Date: 2018
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Journal: Journal of hypertension 
Abstract: 
The pulsatile secretion of adrenocortical hormones and a stress reaction occurring when starting adrenal vein sampling (AVS) can affect the selectivity and also the assessment of lateralization when sequential blood sampling is used. We therefore tested the hypothesis that a simulated sequential blood sampling could decrease the diagnostic accuracy of lateralization index for identification of aldosterone-producing adenoma (APA), as compared with bilaterally simultaneous AVS.
URI: http://hdl.handle.net/20.500.12857/115789
ISSN: 02636352
DOI: 10.1097/HJH.0000000000001564
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