Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12857/115805
Title: PAI-1 and protein C as early markers of veno-occlusive disease in patients treated for Wilms tumor
Authors: Cesaro, Simone 
Mauro, Margherita
Sattin, Giulia
Sartori, Maria Teresa 
Saggiorato, Graziella 
Paratella, Alessandra
Tridello, Gloria 
Bisogno, Gianni 
Keywords: PAI-1;Wilms tumor;liver toxicity;protein C;veno-occlusive disease
Keywords Plus: SINUSOIDAL OBSTRUCTION SYNDROME;SYNDROME/VENO-OCCLUSIVE DISEASE;STEM-CELL TRANSPLANTATION;SEVERITY CRITERIA;EUROPEAN-SOCIETY;OPEN-LABEL;DIAGNOSIS;LIVER;CLASSIFICATION;CHEMOTHERAPY
Mesh headings: Antineoplastic Combined Chemotherapy Protocols;Hepatic Veno-Occlusive Disease;Neoplasm Proteins;Plasminogen Activator Inhibitor 1;Protein C;Wilms Tumor
Secondary Mesh headings: Adolescent;Child;Child, Preschool;Female;Humans;Incidence;Infant;Male;Prospective Studies;Retrospective Studies
Issue Date: 2019
Publisher: WILEY
Journal: Pediatric blood & cancer 
Abstract: 
Hepatic veno-occlusive (VOD) disease has been described in hematopoietic stem cell transplantation (HSCT), solid tumors, and acute lymphoblastic leukemia. The incidence of VOD in Wilms tumor (WT) ranges from 1.2% to 8%. The diagnosis of VOD is clinical, and there are no validated laboratory biomarkers.
URI: http://hdl.handle.net/20.500.12857/115805
ISSN: 15455009
DOI: 10.1002/pbc.27695
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