Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12857/115842
Title: Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group
Authors: Ferrari, Andrea
Chi, Yueh-Yun
De Salvo, Gian Luca 
Orbach, Daniel
Brennan, Bernadette
Randall, R Lor
McCarville, M Beth
Black, Jennifer O
Alaggio, Rita 
Hawkins, Douglas S
Bisogno, Gianni 
Spunt, Sheri L
Keywords: Adjuvant treatment;Low risk;Pediatric sarcoma;Surgery;Synovial sarcoma
Keywords Plus: LONG-TERM OUTCOMES;SINGLE INSTITUTION;RE-EXCISION;EXPERIENCE;CHILDHOOD;PROGNOSIS;AGE;EPIDEMIOLOGY;SURVEILLANCE;RADIOTHERAPY
Mesh headings: Sarcoma, Synovial
Secondary Mesh headings: Adolescent;Chemoradiotherapy, Adjuvant;Child;Child, Preschool;Extremities;Humans;Kaplan-Meier Estimate;Neoplasm Recurrence, Local;Prospective Studies;Risk Factors;Salvage Therapy
Issue Date: 2017
Publisher: ELSEVIER SCI LTD
Journal: European journal of cancer (Oxford, England : 1990) 
Abstract: 
Multimodal risk-adapted treatment is used in paediatric protocols for synovial sarcoma (SS). Retrospective analyses suggest that low-risk SS patients can be safely treated with surgery alone, but no prospective studies have confirmed the safety of this approach. This analysis pooled data from the two prospective clinical trials to assess outcomes in SS patients treated with a surgery-only approach and to identify predictors of treatment failure.
URI: http://hdl.handle.net/20.500.12857/115842
ISSN: 09598049
DOI: 10.1016/j.ejca.2017.03.003
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