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|Title:||Prostatic stromal sarcoma in an adolescent: the role of chemotherapy||Authors:||Cavaliere, Elena
|Keywords:||chemotherapy;prostatic neoplasm;specialized prostatic stroma;stromal sarcoma||Issue Date:||27-Oct-2014||Journal:||Rare tumors||Abstract:||
Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.
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