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|Title:||Long-term care of transplant recipients: de novo neoplasms after liver transplantation||Authors:||Burra, Patrizia
|Keywords:||De novo neoplasms;Immunosuppression;Liver transplantation;Outcome||Keywords Plus:||POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDERS;SOLID-ORGAN TRANSPLANTATION;SINGLE-CENTER EXPERIENCE;HEPATOCELLULAR-CARCINOMA;RISK-FACTORS;SKIN-CANCER;KAPOSI-SARCOMA;MALIGNANCY;MULTICENTER;SURVIVAL||Mesh headings:||Liver Transplantation;Neoplasms||Secondary Mesh headings:||Humans;Immunosuppressive Agents;Long-Term Care;Risk Factors;Transplant Recipients||Issue Date:||2018||Publisher:||LIPPINCOTT WILLIAMS & WILKINS||Journal:||Current opinion in organ transplantation||Abstract:||
Since the first liver transplantation in the early 1960s, there have been significant improvements in the recipients' long-term outcome. Patients who have undergone transplantation are exposed to a high risk of developing neoplastic disease, not only because of their chronic immunosuppression, but also related to physiological aging, lifestyle, chronic viral infections, liver disease cause, and carcinogenic immunosuppressants. The present review covers the latest and most relevant data on de novo neoplasms after liver transplantation, and discusses their implications for clinical practice.
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