Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12857/126927
Title: Acutely developing, spurious anaemia without actual blood loss. A paradigmatic case report
Authors: Lippi, Giuseppe 
Cervellin, Gianfranco 
Keywords: anaemia;case report;errors;posture;preanalytical variability
Keywords Plus: EFLM WORKING GROUP;LABORATORY MEDICINE;PREANALYTICAL PHASE;CLINICAL-CHEMISTRY;EUROPEAN FEDERATION;CROATIAN SOCIETY;POSTURE;PLASMA;BIOCHEMISTRY;PHLEBOTOMY
Mesh headings: Anemia;Phlebotomy;Posture
Secondary Mesh headings: Abdominal Pain;Acute Disease;Blood Chemical Analysis;Diagnosis, Differential;Emergency Service, Hospital;Female;Humans;Middle Aged;Reproducibility of Results;Sensitivity and Specificity;Supine Position
Issue Date: 15-Jun-2017
Publisher: CROATIAN SOC MEDICAL BIOCHEMISTS
Journal: Biochemia medica 
Abstract: 
We describe the case of a 55-year old women admitted at night to the emergency department (ED), complaining for acute abdominal pain lasting for nearly 5 hours. A first blood testing, performed immediately after admission, revealed mild anaemia. A second blood sample, drawn two hours after admission, revealed a considerable decrease of haemoglobin, haematocrit, total white blood cell and platelet counts (between 10-15% reduction). Abdominal ultrasonography was normal and the patient had no signs or symptoms of internal or external haemorrhage. Pre-analytical and analytical errors were accurately excluded. No infusion therapy was administered. After thoughtful discussing the sequence of events, it was ascertained that the first set of blood samples was drawn with the patient in seated position, immediately after ED admission (i.e., approximately 1 min passed from standing to seated position before venipuncture), whereas the second set of blood samples was drawn with the patient lying for two hours in supine position. This case report highlights the importance of standardizing patient position before venous blood collection, along with the crucial role played by cooperation and communication between laboratory and clinical wards for identifying and troubleshooting potential causes of spurious results of in vitro diagnostic testing.
URI: http://hdl.handle.net/20.500.12857/126927
ISSN: 1330-0962
DOI: 10.11613/BM.2017.045
Appears in Collections:Articles

Show full item record

PubMed Central
Citations 50

1
Last Week
0
Last month
0
checked on May 3, 2021

SCOPUSTM   
Citations 50

5
checked on Aug 31, 2020

WEB OF SCIENCETM
Citations

6
checked on Nov 26, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.