Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12857/127879
Title: Embryo quality before and after slow freezing: Viability, implantation and pregnancy rates in 627 single frozen-thawed embryo replacement cycles following failure of fresh transfer
Authors: Capodanno, Francesco
De Feo, Gaetano
Gizzo, Salvatore 
Nicoli, Alessia
Palomba, Stefano
La Sala, Giovanni Battista
Keywords: ART;Embryos;Freezing;Infertility;Outcome
Keywords Plus: EARLY CLEAVAGE-STAGE;CRITICAL-APPRAISAL;CRYOPRESERVATION;VITRIFICATION;IVF;FERTILIZATION;NUMBER;MORPHOLOGY;SURVIVAL;OUTCOMES
Mesh headings: Cryopreservation;Embryo Implantation;Embryo Transfer;Reproductive Techniques, Assisted
Secondary Mesh headings: Adult;Female;Humans;Pregnancy;Pregnancy Rate;Retrospective Studies
Issue Date: Jun-2016
Publisher: INST ANIMAL REPRODUCTION FOOD RESEARCH
Journal: Reproductive biology 
Abstract: 
Frozen embryo transfer cycles are now common practice, however, various aspects regarding the potential of frozen embryos remain unclear. The main goal of the present study was to assess embryo quality before and after slow freezing procedure, and more specifically blastomere loss and embryo quality as indicator of viability. A single center retrospective analysis of single frozen-thawed embryo replacements (s-FER) was performed. The embryo quality before and after slow freezing and thawing, implantation, and pregnancy rates were recorded. One hundred and twenty seven s-FER were included in the final analysis. The probability of achieving an ongoing pregnancy was significantly associated with embryo quality and the percentage of blastomere loss after thawing. Considering thawed embryos, a non-significant difference in term of implantation rate was observed, regardless to their post-thawing quality and the percentage of blastomeres loss. In conclusion, current data suggest that thawed embryos are capable of implantation regardless of their morphological quality and the degree of cryoinjury sustained.
URI: http://hdl.handle.net/20.500.12857/127879
ISSN: 1642431X
DOI: 10.1016/j.repbio.2016.03.002
Appears in Collections:Articles

Show full item record

PubMed Central
Citations 50

3
Last Week
0
Last month
0
checked on Nov 28, 2021

SCOPUSTM   
Citations 5

3
checked on Aug 31, 2020

WEB OF SCIENCETM
Citations

4
checked on Nov 26, 2021

Page view(s) 1

3
checked on Nov 29, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.